HelixlyAI Genome Report Prepared for Sample Subject
Report ID HX-2026-0042 · synthetic
Methylation & Metabolism · Document 10 of 24

Alcohol Flush (ALDH2)

Sample Subject's acetaldehyde clearance and the alcohol-flush response, read from ALDH2 and ADH1B genotype. All values below are synthetic and for demonstration only.

2 findings 1 Tier 1 1 Tier 3 Reviewed 2026-01-15

Provenance

Data Provenance verified chain
Document
Alcohol Flush (ALDH2)
Source assembly
GRCh37 (hg19)
Source file SHA-256
0000a1b2c3d4e5f6…4b5c6d7e
Supersedes
prior v1 · SHA 1111f0e9…
Evidence sources
PubMed, dbSNP
Access date
2026-01-15

Per-Gene Findings

Filter:

ALDH2 — Flush Allele Present

Aldehyde dehydrogenase 2 · acetaldehyde clearance
PubMedTier 1
rs671 12:112,241,766 GA

The GA genotype carries one ALDH2*2 allele. This allele reduces acetaldehyde clearance and produces the alcohol-flush response after alcohol intake.

Source: PubMed PMID 19320627 ↗ · dbSNP rs671 ↗

ADH1B — Reference Allele

Alcohol dehydrogenase 1B · ethanol oxidation
dbSNPTier 3
rs1229984 4:100,239,319 CC

The CC genotype is the reference ADH1B allele. This sample carries typical ADH1B ethanol-oxidation activity at this position.

Source: dbSNP rs1229984 ↗

Genotype Table

Variants evaluated in this document — synthetic
rsIDchr:posGenotypeGeneSignificance
rs67112:112,241,766GAALDH2Tier 1
rs12299844:100,239,319CCADH1BTier 3
Consult your prescribing clinician. This HelixlyAI report is a synthetic demonstration generated from a consumer DNA export. It is not a diagnosis, prescription, or substitute for professional medical advice. Do not start, stop, or change any medication based on this document. Genotype is one of many factors influencing drug response.